offMetro’s NYC to Boston Transportation Guide
By Bus
megabus.com
Depart: Most buses depart from the south side of 34th Street between 11 & 12th Avenues convenient to 34th Street Penn Station train service and M34 NY Transit cross town buses.
Arrive: South Station
Duration: Approx 4hrs
Cost: $1-$35 each way, depending on when you purchase your ticket
Notes: Free wifi & power outlets, seat belts, reclining seats, frequent daily departures. Cheap tickets if you purchase ahead of time.
Greyhound
Depart: New York Port Authority
Arrive: South Station Bus Terminal, 700 Atlantic Ave
Duration: 4 – 5 hours
Cost: $15-$40 each way, with options to upgrade your ticket to include more than one piece of luggage.
LimoLiner
Depart: Hilton New York Hotel – 6th Ave at 53rd St
Arrive: Hilton Boston Back Bay Hotel – Dalton and Boylston Street at the Prudential Center
Duration: 4 – 5 hours
Cost: $99 one way
Notes: A luxury bus line that includes 28 Leather Seats, Meal, Beverage and Snack Service, Direct TV, DVD movies, luxury bathroom, professional onboard attendant, and more.
By Train
Amtrak Acela
Depart: New York Penn Station
Arrive: Boston South Station, 2 South Station Summer St. or Back Bay, 145 Dartmouth St.
Duration: 3 hours 40 minutes
Cost: $125-$215 one way
Notes: Quickest way to get to Boston, but also the most expensive. Average price is about $130 one way.
Amtrak Regional
Depart: New York Penn Station
Arrive: Boston South Station, 2 South Station Summer St. or Back Bay, 145 Dartmouth St.
Duration: 4 hours to 4 hours, 15 minutes
Cost: $83 – $162 one way
Notes: Usually cheaper than the Acela Express, and not too much longer. However, when you are traveling at a time when no traffic is expected, consider one of the bus options which could get you there in the same time, and at a fraction of the cost.
You can find and compare all bus & train travel options from New York to Boston on Wanderu.
Sarah Knapp is a Brooklyn based entrepreneur whose love for the outdoors and community building led her to the October 2013 creation of OutdoorFest. She has a BA in History, is a Wilderness First Responder and a NY state hiking, camp and boating guide. Her proudest achievement to date is reading the Aeneid in Latin. 
Allison was one of our first top writers and Chief Editor but is no longer working with offMetro. Allison is a native New Yorker, who has lived in Rome, Tuscany, Melbourne, Toronto and Los Angeles. She frequently contributed travel pieces to Family Travel Forum, using her own children as guinea pigs as they travel the globe. She never missed a chance to sample local delicacies, as her love for travel goes hand-in-hand with her love for food and wine. 
Josh Laskin is a freelance travel writer and photographer based in the White Mountains of New Hampshire. When he is not at work or on the road, you can find him in the mountains snowboarding, climbing, hiking, fly fishing, mountain biking, and eating bagel bites.
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Kate E. O’Hara is a New York based freelance writer and photographer who loves all things food—especially the people who make it and market it. Her writing aims to capture the essence of the food experience; the stories that go well beyond a plate of ingredients. In addition to her love of food, Kate is also known to have a hankering for red wine and craft beer. You can also find Kate on Instagram