Manhattan to Pittsburgh Public Transportation Advisor

Pittsburgh

How to get there:

Bus lines

megabus.com
Depart: 34th St. between 11th Ave and 12th Ave.
Arrive: 10th St and Penn Ave.
Duration:
8 hrs
Cost:
$1-$50 one way
Notes:
Free wifi & power outlets, seat belts, frequent daily departures. 

Great Wall Bus
Depart: 34 Canal Street
Arrive: Pittsburgh
Duration: 6.5h
Cost: $40-$50 one way
Frequency: Bus departs 5:20pm every day

Greyhound
Depart: New York Port Authority
Arrive: Pittsburgh
Duration: 8h 35m – 10 h 55m
Cost: $37-$61 one wa

Pittsburgh via Train

Amtrak Pennsylvanian
Depart: New York Penn Station
Arrive: Pittsburgh
Duration: 9h 15m
Cost: $81 – $189
Notes: Amtrak offers another train route to Pittsburgh, however it involves transferring trains.